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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Minocycline hydrochloride/3268/50/50 mg
产品编号:3268/50
市  场 价:¥1900.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$95.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Minocycline hydrochloride/3268/50/50 mg
商品介绍
Description:Antibiotic.Displaysneuroprotectiveeffects
ChemicalName:[4S-(4α,4aα,5aα,12aα)]-4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a,tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Tetracyclineantibiotic.Displaysneuroprotective,antiapoptotic,anti-inflammatoryandantimicrobialeffects.Actsasamatrixmetalloproteinase(MMP)inhibitor;attenuatesdiseaseseverityinmousemodelsofmultiplesclerosis.Orallyactiveandbrainpenetrant.Allowsformationofextendedpluripotentstem(EPS)cellsincombinationwithCHIR99021(Cat.No.4423),(S)-(+)-Dimethindenemaleate(Cat.No.1425)andhumanleukemiainhibitoryfactor.

TechnicalData

M.Wt493.94
FormulaC23H27N3O7.HCl
StorageDesiccateat+4°C
Purity≥98%(HPLC)
CASNumber13614-98-7
PubChemID54685925
InChIKeyWTJXVDPDEQKTCV-VQAITOIOSA-N
SmilesNC(C4=C(O)[C@@H](N(C)C)[C@@]3([H])[C@](C4=O)(O)C(O)=C2C(C1=C(O)C=CC(N(C)C)=C1C[C@]([H])2C3)=O)=O.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO49.39100
water12.3525

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight493.94.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.02mL10.12mL20.25mL
5mM0.4mL2.02mL4.05mL
10mM0.2mL1.01mL2.02mL
50mM0.04mL0.2mL0.4mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet