请使用支持JavaScript的浏览器!
主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Maritoclax/5368/50/50 mg
产品编号:5368/50
市  场 价:¥16100.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$805.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Maritoclax/5368/50/50 mg
商品介绍
Description:Mcl-1inhibitor;proapoptotic
ChemicalName:1,1'-(4,4',5,5'-Tetrachloro[1,3'-bi-1H-pyrrole]-2,2'-diyl)bis[1-2-hydroxyphenyl)methanone
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Mcl-1inhibitor;disruptsMcl-1-BiminteractionandinducesMcl-1proteasomaldegradation.ExhibitsnoeffectonBcl-XL-Biminteraction.SelectivelyinducesapoptosisinMcl-1-dependentK562leukemiacells.SensitizesK562andRajicellstoABT-737-inducedapoptosis.

TechnicalData

M.Wt510.15
FormulaC22H12Cl4N2O4
StorageStoreat-20°C
Purity≥97%(HPLC)
CASNumber1227962-62-0
PubChemID24797083
InChIKeyQYPJBTMRYKRTFG-UHFFFAOYSA-N
SmilesClC1=C(Cl)C(N2C(C(C4=C(O)C=CC=C4)=O)=CC(Cl)=C2Cl)=C(C(C3=C(O)C=CC=C3)=O)N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO51.01100
ethanol25.5150

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight510.15.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.96mL9.8mL19.6mL
5mM0.39mL1.96mL3.92mL
10mM0.2mL0.98mL1.96mL
50mM0.04mL0.2mL0.39mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet