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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/ML 311/5733/50/50 mg
产品编号:5733/50
市  场 价:¥14700.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$735.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/ML 311/5733/50/50 mg
商品介绍
Description:InhibitsMcl-1-BIMinteraction
ChemicalName:7-[(4-Ethyl-1-piperazinyl)[4-(trifluoromethyl)phenyl]methyl]-8-quinolinol
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InhibitsMcl1-BIMinteraction.InhibitsviABIlityofMcl1-dependenttumorcelllines.InducescelldeathanddecreasedspheroidformationinHer2positivebreastcancercells.

TechnicalData

M.Wt415.45
FormulaC23H24F3N3O
StorageStoreat-20°C
Purity≥99%(HPLC)
CASNumber315698-17-0
PubChemID3384730
InChIKeyNGAPBLRRJSKIRT-UHFFFAOYSA-N
SmilesCCN(CC1)CCN1C(C2=CC=C(C(F)(F)F)C=C2)C3=C(O)C4=NC=CC=C4C=C3

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO20.7750
ethanol20.7750

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight415.45.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.41mL12.04mL24.07mL
5mM0.48mL2.41mL4.81mL
10mM0.24mL1.2mL2.41mL
50mM0.05mL0.24mL0.48mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet