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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Leukadherin 1/4921/10/10 mg
产品编号:4921/10
市  场 价:¥2180.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$109.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Leukadherin 1/4921/10/10 mg
商品介绍
Description:AllostericactivatorofCD11b/CD18
ChemicalName:4-[(5-[[4-Oxo-3-(phenylmethyl)-2-thioxo-5-thiazolidinylidene]methyl]-2-furanyl]benzoicacid
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

AllostericactivatorofCD11b/CD18.IncreasesCD11b/CD18-dependentcelladhesiontofibrinogen(EC50=4μM).Decreasesleukocytemotilityandtransendothelialmigration;reducesinflammation.Alsoactivatescomplementreceptor3(CR3),andpromotesCR3-dependentleukocyteadhesiontofibrinogen-coatedsurfaces.

TechnicalData

M.Wt421.49
FormulaC22H15NO4S2
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber344897-95-6
PubChemID5342077
InChIKeyAEZGRQSLKVNPCI-UNOMPAQXSA-N
SmilesS=C(N(CC3=CC=CC=C3)C2=O)S/C2=CC1=CC=C(C4=CC=C(C(O)=O)C=C4)O1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO4.2110mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight421.49.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.37mL11.86mL23.73mL
5mM0.47mL2.37mL4.75mL
10mM0.24mL1.19mL2.37mL
50mM0.05mL0.24mL0.47mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet