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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/KS 176/4169/50/50 mg
产品编号:4169/50
市  场 价:¥16100.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$805.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/KS 176/4169/50/50 mg
商品介绍
Description:SelectiveBCRPinhibitor
ChemicalName:N-[4-(2-Hydroxyethyl)phenyl]-2-[(4-nitrobenzoyl)amino]benzamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectiveinhibitorofthebreastcancerresistanceprotein(BCRP)multidrugtransporter(IC50valuesare0.59and1.39μMinPheoAandHoechst33342assaysrespectively).DisplaysnoinhibitoryactivityagainstP-gporMRP1.

CompoundLibraries

KS176isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt405.4
FormulaC22H19N3O5
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber1253452-78-6
PubChemID49779726
InChIKeyLTWQQWSXYYXVGA-UHFFFAOYSA-N
SmilesOCCC1=CC=C(NC(C2=C(NC(C3=CC=C([N+]([O-])=O)C=C3)=O)C=CC=C2)=O)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO40.54100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight405.4.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.47mL12.33mL24.67mL
5mM0.49mL2.47mL4.93mL
10mM0.25mL1.23mL2.47mL
50mM0.05mL0.25mL0.49mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet