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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/endo-IWR 1/3532/50/50 mg
产品编号:3532/50
市  场 价:¥11580.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$579.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/endo-IWR 1/3532/50/50 mg
商品介绍
Description:Wnt/β-cateninsignalinginhibitor;axinstABIlizer
ChemicalName:[(3aR*,4S*,7R*,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InhibitorofWntsignaling.InducesanincreaseinAxin2proteinlevels;promotesβ-cateninphosphorylationbystabilizingAxin-scaffoldeddestructioncomplexes.Negativecontrolexo-IWR(Cat.No.3947)available.

CompoundLibraries

endo-IWR1isalsoofferedaspartoftheTocriscreenPlusandTocriscreenStemCellToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt409.44
FormulaC25H19N3O3
StorageStoreatRT
Purity≥98%(HPLC)
CASNumber1127442-82-3
PubChemID90488854
InChIKeyMFEADGGBEDIZRE-MGIYQXMMSA-N
Smiles[H][C@]13[C@](C(N(C4=CC=C(C(NC5=CC=CC6=C5N=CC=C6)=O)C=C4)C3=O)=O)([H])[C@H]2C=C[C@@H]1C2.[H][C@@]79[C@@](C(N(C%10=CC=C(C(NC%11=CC=CC%12=C%11N=CC=C%12)=O)C=C%10)C9=O)=O)([H])[C@@H]8C=C[C@H]7C8

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO40.94100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight409.44.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.44mL12.21mL24.42mL
5mM0.49mL2.44mL4.88mL
10mM0.24mL1.22mL2.44mL
50mM0.05mL0.24mL0.49mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet