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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/INCA-6/2162/10/10 mg
产品编号:2162/10
市  场 价:¥2580.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>蛋白酶类>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$129.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/INCA-6/2162/10/10 mg
商品介绍
Description:Inhibitorofcalcineurin-substrateassociation
ChemicalName:9,10-Dihydro-9,10[1',2']-benzenoanthracene-1,4-dione
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InhibitorofinteractionbetweencalcineurinanditssubstratenuclearfactorofactivatedTcells(NFAT);blocksatthesubstraterecognitionsitebutnotatthecatalyticsite(Kd=0.8mM).InhibitsNFATdephosphorylationandnuclearimport.AlsopreventsinductionofcytokinemRNAsthataredownstreamtargetsofNFAT.

CompoundLibraries

INCA-6isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt284.31
FormulaC20H12O2
StorageStoreatRT
Purity≥98%(HPLC)
CASNumber3519-82-2
PubChemID230748
InChIKeyGCHPUOHXXCNSQL-UHFFFAOYSA-N
SmilesO=C1C=CC(=O)C2=C1C1C3=C(C=CC=C3)C2C2=C1C=CC=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO5.6920

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight284.31.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.52mL17.59mL35.17mL
5mM0.7mL3.52mL7.03mL
10mM0.35mL1.76mL3.52mL
50mM0.07mL0.35mL0.7mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet