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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Heclin/5433/10/10 mg
产品编号:5433/10
市  场 价:¥2580.00
场      地:美国(厂家直采)
产品分类: 分子类>核酸酶类>连接酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$129.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Heclin/5433/10/10 mg
商品介绍
Description:HECTE3ubiquitinligaseinhibitor
ChemicalName:N-(4-Acetylphenyl)-3-(5-ethyl-2-furanyl)-2-propenamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

HECTE3ubiquitinligaseinhibitor;inhibitsNedd4,Smurf2andWWP1(IC50valuesare6.3,6.8and6.9μMrespectively).SelectiveforHECT-mediatedoverRING-mediatedubiquitination.

CompoundLibraries

HeclinisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt283.32
FormulaC17H17NO3
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber890605-54-6
PubChemID7464118
InChIKeySPTWXRJNCFIDRQ-ZHACJKMWSA-N
SmilesCC(C1=CC=C(NC(/C=C/C2=CC=C(CC)O2)=O)C=C1)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO28.33100
ethanol14.1750

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight283.32.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.53mL17.65mL35.3mL
5mM0.71mL3.53mL7.06mL
10mM0.35mL1.76mL3.53mL
50mM0.07mL0.35mL0.71mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet