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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Ginkgolic Acid/6326/10/10 mg
产品编号:6326/10
市  场 价:¥2700.00
场      地:美国(厂家直采)
产品分类: 分子类>核酸酶类>连接酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$135.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Ginkgolic Acid/6326/10/10 mg
商品介绍
Description:InhibitsSUMOylationbybindingE1
ChemicalName:2-Hydroxy-6-(8Z)-8-pentadecenylbenzoicacid
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InhibitorofSUMOylation(IC50=3μM).DirectlybindsE1andinhibitsformationofE1-SUMOintermediate.Protectsagainstamyloidβ-inducedimpairmentofneurotransmissionandsynapticplasticity.AlsosuppressesCD44andMMP14expressioninbreastcancercells,eliminatingcancerstemcellsandinhibitingtumOrigenesis.

TechnicalData

M.Wt346.5
FormulaC22H34O3
StorageStoreat-20°C
Purity≥97%(HPLC)
CASNumber22910-60-7
PubChemID5281858
InChIKeyYXHVCZZLWZYHSA-FPLPWBNLSA-N
SmilesCCCCCC/C=CCCCCCCCC1=C(C(O)=CC=C1)C(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO34.65100
ethanol34.65100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight346.5.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.89mL14.43mL28.86mL
5mM0.58mL2.89mL5.77mL
10mM0.29mL1.44mL2.89mL
50mM0.06mL0.29mL0.58mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet