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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/WIN 55,212-3 mesylate/2327/50/50 mg
产品编号:2327/50
市  场 价:¥10700.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$535.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/WIN 55,212-3 mesylate/2327/50/50 mg
商品介绍
Description:CB2antagoNIST/CB1partialinverseagonist;enantiomerofWIN55,212-2(Cat.No.1038)
AlternativeNames:(S)-(-)-WIN55,212
ChemicalName:[(3S)-2,3-Dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenyl-methanonemonomethanesulfonate
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Novel,lowpotencyCB2receptorsilentantagonistandCB1receptorpartialinverseagonist.CompetitivelyantagonizeseffectsofCP55,940(pA2=6.1)andSR144528(pEC50=5.3)atCB2receptorsandactsasapartialinverseagonistatCB1receptors(pIC50=5.5).DisplaysmodestactivityathumanmelatoninMT1andmuscarinicM4receptors,butisselectiveoverseveralotherGPCRs.

TechnicalData

M.Wt522.61
FormulaC27H26N2O3.CH3SO3H
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber131543-25-4
PubChemID11613341
InChIKeyFSGCSTPOPBJYSX-BDQAORGHSA-N
SmilesCS(O)(=O)=O.CC1=C(C(=O)C2=CC=CC3=C2C=CC=C3)C2=CC=CC3=C2N1[C@@H](CN1CCOCC1)CO3

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO52.26100mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight522.61.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.91mL9.57mL19.13mL
5mM0.38mL1.91mL3.83mL
10mM0.19mL0.96mL1.91mL
50mM0.04mL0.19mL0.38mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet