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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/GSK J2/4688/50/50 mg
产品编号:4688/50
市  场 价:¥16500.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$825.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/GSK J2/4688/50/50 mg
商品介绍
Description:InactiveisomerofGSKJ1(Cat.No.4593)
ChemicalName:N-[2-(3-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanineethylester
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InactivecontrolofGSKJ1(CatNo.4593)(IC50>100μMforinhibitionofJMJD3/UTX).Cellpermeableesterderivative,GSKJ5(Cat.No.4689),alsoavailable.

LicensingInformation

ThiscompoundissuppliedinconjunctionwiththeStructuralGenomicsConsortium.ForfurtherdetailsofGSKJ2,aninactiveisomerofGSKJ1,pleasevisittheGSKJ1probesummaryontheSGCwebsite.

CompoundLibraries

GSKJ2isalsoofferedaspartoftheTocriscreenPlusandTocriscreenEpigeneticsToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt389.45
FormulaC22H23N5O2
StorageDesiccateatRT
Purity≥98%(HPLC)
CASNumber1394854-52-4
PubChemID73010924
InChIKeyLJIFOCRGDDQFJF-UHFFFAOYSA-N
SmilesO=C(CCNC1=NC(C2=CC=CN=C2)=NC(N3CCC(C=CC=C4)=C4CC3)=C1)O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
1eq.HCl19.4750
DMSO38.94100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight389.45.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.57mL12.84mL25.68mL
5mM0.51mL2.57mL5.14mL
10mM0.26mL1.28mL2.57mL
50mM0.05mL0.26mL0.51mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet