请使用支持JavaScript的浏览器!
主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/GSK 4112/3663/10/10 mg
产品编号:3663/10
市  场 价:¥2980.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$149.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/GSK 4112/3663/10/10 mg
商品介绍
Description:SelectiveRev-ErbαagoNIST
AlternativeNames:SR6452
ChemicalName:1,1-Dimethylethyl-N-[(4-chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl])glycinate
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveRev-Erbαagonist(EC50=250nM).Enhancesrecruitmentofnuclearreceptorco-repressor(NCoR)peptidetoRev-Erbα;causesacutesuppressionofBMAl1genetranscription.InducesphaseshiftsinthecircADIanclock.

TechnicalData

M.Wt396.89
FormulaC18H21ClN2O4S
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber1216744-19-2
PubChemID50905018
InChIKeyWYSLOKHVFKLWOU-UHFFFAOYSA-N
SmilesCC(C)(C)OC(CN(CC2=CC=C(Cl)C=C2)CC1=CC=C([N+]([O-])=O)S1)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO9.9225

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight396.89.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.52mL12.6mL25.2mL
5mM0.5mL2.52mL5.04mL
10mM0.25mL1.26mL2.52mL
50mM0.05mL0.25mL0.5mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet