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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/GSA 10/4918/10/10 mg
产品编号:4918/10
市  场 价:¥3780.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$189.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/GSA 10/4918/10/10 mg
商品介绍
Description:SmoreceptoragoNIST
ChemicalName:4-[[(1-Hexyl-1,2-dihydro-2-oxo-3-quinolinyl)carbonyl]amino]benzoicacidpropylester
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Smoothened(Smo)receptoragonist(EC50=1.2μM).Doesnotrecognizetheclassiccyclopamine(Cat.No.1623)bindingsite.DoesnotpromoteSmotranslocationtotheprimarycilium;isstronglypotentiatedbyforskolinandcholeratoxin.PromotesdifferentiationofmultipotentmesenchymalProgenitorcellsintoosteoblasts.

TechnicalData

M.Wt450.53
FormulaC26H30N2O5
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber300833-95-8
PubChemID54683103
InChIKeyMDLUYYGRCGDKGL-UHFFFAOYSA-N
SmilesOC(C1=CC=CC=C1N2CCCCCC)=C(C(NC3=CC=C(C(OCCC)=O)C=C3)=O)C2=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO2.255mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight450.53.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.22mL11.1mL22.2mL
5mM0.44mL2.22mL4.44mL
10mM0.22mL1.11mL2.22mL
50mM0.04mL0.22mL0.44mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet