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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/GRI 977143/4779/10/10 mg
产品编号:4779/10
市  场 价:¥3780.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$189.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/GRI 977143/4779/10/10 mg
商品介绍
Description:SelectiveLPA2receptornon-lipidagoNIST
ChemicalName:2-[[3-(1,3-dioxo-1H-benz[de]isoquinolin-2(3H)-yl)propyl]thio]benzoicacid
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectivelysophosphatidicacid2(LPA2)receptornon-lipidagonist(EC50=3.3μM).DoesnotactivateotherLPAGPCRsatconcentrationsupto10μM.Antiapoptotic;inhibitsactivationofcaspases3,7,8and9,BaxtranslocationandPARP-1cleavage.ActivatesERK1/2survivalpathway.

TechnicalData

M.Wt391.44
FormulaC22H17NO4S
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber325850-81-5
PubChemID3114900
InChIKeyGMVZUCHUOYUMLL-UHFFFAOYSA-N
SmilesO=C(C2=CC=CC3=CC=CC(C4=O)=C23)N4CCCSC1=CC=CC=C1C(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO39.14100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight391.44.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.55mL12.77mL25.55mL
5mM0.51mL2.55mL5.11mL
10mM0.26mL1.28mL2.55mL
50mM0.05mL0.26mL0.51mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet