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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/GA3-AM/5407/10/10 mg
产品编号:5407/10
市  场 价:¥1300.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$65.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/GA3-AM/5407/10/10 mg
商品介绍
Description:Gibberellin-analog(GA3)chemicaldimerizer;cellpermeable
ChemicalName:(1S,2S,4aR,4bR,7S,9aS,10S,10aR)-1,2,4b,5,6,7,8,9,10,10a-Decahydro-2,7-dihydroxy-1-methyl-8-methylene-13-oxo-4a,1-(epoxymethano)-7,9a-methanobenz[a]azulene-10-aceticacid(acetyloxy)methylester
Purity:≥90%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Gibberellin-analog(GA3)chemicaldimerizer;inducesrapiddimerizationofGAIsandGID1.GA3-AMcrossestheplasmamembrane,iscleavedbycytosolicesterasereleasingGA3,whichthenbindsGID1-thiscomplextheninturnformsacomplexwithGAI;thissystemworksonatimescaleofseconds(EC50=310nM).GA3andrapamycin(Cat.No.1292)chemicallyinducIBLedimerizationsystemsareorthogonal.Cellpermeable.

TechnicalData

M.Wt418.44
FormulaC22H26O8
StorageStoreat-20°C
Purity≥90%(HPLC)
CASNumber1373154-68-7
PubChemID56835187
InChIKeyIVIYFJSPDLOPEX-SEWSRMJOSA-N
Smiles[H][C@@]12[C@@](C[C@@]3(O)CC2)(CC3=C)[C@@H](C(OCOC(C)=O)=O)[C@]4([H])[C@@]5(C)[C@@H](O)C=C[C@]41OC5=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO41.84100
ethanol41.84100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight418.44.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.39mL11.95mL23.9mL
5mM0.48mL2.39mL4.78mL
10mM0.24mL1.19mL2.39mL
50mM0.05mL0.24mL0.48mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet