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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Ferrostatin 1/5180/50/50 mg
产品编号:5180/50
市  场 价:¥13300.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$665.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Ferrostatin 1/5180/50/50 mg
商品介绍
Description:Selectiveinhibitoroferastininducedferroptosis
ChemicalName:Ethyl3-amino-4-(cyclohexylamino)benzoate
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectiveinhibitoroferastininducedferroptosis(EC50=60nM).SpecificallyinhibitsRasselectivelethalcompound-induceddeath,butnotcelldeathinducedbyotheroxidativelethalcompoundsandapoptosis-inducingagents.Inhibitsferroptosisincancercells;alsoinhibitsglutamate-inducedcelldeathinorganotypicratbrainslices.Preventserastininducedaccumulationofcytosolicandlipidreactiveoxygenspecies.

CompoundLibraries

Ferrostatin1isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt262.35
FormulaC15H22N2O2
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber347174-05-4
PubChemID4068248
InChIKeyUJHBVMHOBZBWMX-UHFFFAOYSA-N
SmilesO=C(OCC)C1=CC(N)=C(NC2CCCCC2)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO26.23100
ethanol26.23100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight262.35.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.81mL19.06mL38.12mL
5mM0.76mL3.81mL7.62mL
10mM0.38mL1.91mL3.81mL
50mM0.08mL0.38mL0.76mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet