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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/FH 535/4344/50/50 mg
产品编号:4344/50
市  场 价:¥7500.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$375.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/FH 535/4344/50/50 mg
商品介绍
Description:InhibitorofWnt/β-cateninsignaling
ChemicalName:2,5-Dichloro-N-(2-methyl-4-nitrophenyl)benzenesulfonamide
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InhibitorofWnt/β-cateninsignalinganddualantagoNISTofPPARγ/δactivity.Suppressesβ-catenin/Tcf-mediatedtranscription;inhibitsβ-cateninandGRIP1recruitmenttoPPARγandδ.Exhibitsantiproliferativeeffectsintransformedcolon,lungandlivercancercelllines.

CompoundLibraries

FH535isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt361.2
FormulaC13H10Cl2N2O4S
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber108409-83-2
PubChemID3463933
InChIKeyAXNUEXXEQGQWPA-UHFFFAOYSA-N
SmilesClC1=CC(S(NC2=C(C)C=C([N+]([O-])=O)C=C2)(=O)=O)=C(Cl)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO27.0975

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight361.2.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.77mL13.84mL27.69mL
5mM0.55mL2.77mL5.54mL
10mM0.28mL1.38mL2.77mL
50mM0.06mL0.28mL0.55mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet