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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/FGIN-1-27/0658/50/50 mg
产品编号:0658/50
市  场 价:¥10700.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$535.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/FGIN-1-27/0658/50/50 mg
商品介绍
Description:Potent,specificligandformitochondrialDBIreceptor
ChemicalName:N,N-Dihexyl-2-(4-fluorophenyl)indole-3-acetamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

BindsspecificallyandwithhighaffinitytothepeptideDBIreceptor(benzodiazepinereceptor)onmitochondrialmembranes,inducingproductionofneurosteroids,whichmodulateGABAreceptors(EC50=3nMforincreaseinproductionofpregnenoloneinglialcells).Thusitreducesanxietywithoutcausingsedation.

CompoundLibraries

FGIN-1-27isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt436.61
FormulaC28H37FN2O
StorageStoreatRT
Purity≥98%(HPLC)
CASNumber142720-24-9
PubChemID132496
InChIKeyVUWXAQFLTSBUDB-UHFFFAOYSA-N
SmilesO=C(N(CCCCCC)CCCCCC)CC2=C(C3=CC=C(F)C=C3)NC1=CC=CC=C12

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO43.66100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight436.61.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.29mL11.45mL22.9mL
5mM0.46mL2.29mL4.58mL
10mM0.23mL1.15mL2.29mL
50mM0.05mL0.23mL0.46mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet