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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/EB 1089/3993/1/1 mg
产品编号:3993/1
市  场 价:¥3700.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$185.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/EB 1089/3993/1/1 mg
商品介绍
Description:VitaminDreceptor(VDR)agoNIST
AlternativeNames:Seocalcitol
ChemicalName:(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4E)-6-Ethyl-6-hydroxy-1-methyl-2,4-octADIen-1-yl]-octahydro-7α-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-cyclohexanediol
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

VitaminDreceptor(VDR)agonist;analogofcalcitriol(Cat.No.2551).Exhibitsanti-tumorandanti-proliferativeactivitywithreducedhypercalcemiceffects.60timesmorepotentininhibitingMCF-7cellgrowthinvitro;alsoshowntoinduceautophagyinMCF-7cells.Reversestheeffectsofparathyroidhormone-relatedprotein(PTHrP).

TechnicalData

M.Wt454.68
FormulaC30H46O3
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber134404-52-7
PubChemID5288149
InChIKeyLVLLALCJVJNGQQ-SEODYNFXSA-N
SmilesC[C@@](CCC2)3[C@](CC[C@@]([H])3[C@@H](/C=C/C=C/C(CC)(O)CC)C)([H])/C2=C/C=C(C[C@@H](O)C[C@@H]1O)C1=C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleinDMSOandinethanol

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight454.68.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.2mL11mL21.99mL
5mM0.44mL2.2mL4.4mL
10mM0.22mL1.1mL2.2mL
50mM0.04mL0.22mL0.44mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet