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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Dolastatin 10 trifluoroacetate/3375/1/1 mg
产品编号:3375/1
市  场 价:¥3580.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$179.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Dolastatin 10 trifluoroacetate/3375/1/1 mg
商品介绍
Description:Tubulinpolymerizationinhibitor
ChemicalName:N,N-Dimethyl-L-valyl-N-[(1S,2R)-2-methoxy-4-[(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-[[(1S)-2-phenyl-1-(2-thiazol)ethyl]amino]propyl]-1-pyrrolidinyl]-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl--valinamidetrifluoroacetate
Purity:≥95%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Tubulinpolymerizationinhibitor.NoncompetitivelyinhibitsbindingofrADIolabeledvincristinetotubulin(Ki=1.4μM)andinducestubulinaggregationinvitro.

TechnicalData

M.Wt899.11
FormulaC42H68N6O6S.CF3CO2H
StorageStoreat-20°C
Purity≥95%(HPLC)
PubChemID9810929
InChIKeyOFDNQWIFNXBECV-VFSYNPLYSA-N
SmilesO=C(C[C@@H](OC)[C@@H](N(C)C([C@H](C(C)C)NC([C@@H](N(C)C)C(C)C)=O)=O)[C@@H](C)CC)N1[C@@]([C@H](OC)[C@@H](C)C(N[C@@H](CC3=CC=CC=C3)C2=NC=CS2)=O)([H])CCC1.FC(C(O)=O)(F)F

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleinDMSO

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight899.11.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.11mL5.56mL11.12mL
5mM0.22mL1.11mL2.22mL
10mM0.11mL0.56mL1.11mL
50mM0.02mL0.11mL0.22mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet