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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Docetaxel/4056/50/50 mg
产品编号:4056/50
市  场 价:¥10700.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$535.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Docetaxel/4056/50/50 mg
商品介绍
Description:MicrotubulestABIlizer
ChemicalName:[2aR-[2aα,4β,4aβ,6β,9α(αR*,βS*),11α,12α,12aα,12bα]]-β-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-hydroxy-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-ylesterbenzenepropanoicacid
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Bindsandstabilizesmicrotubules;leadstocellcyclearrestandapoptosis.Displayssignificantantitumoractivityinovarianandgastrictumors.PreventsmicrotubuledepolymerizationanddisassemblyintheabsenceofGTP.Exhibitscytotoxicactivity.

TechnicalData

M.Wt807.88
FormulaC43H53NO14
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber114977-28-5
PubChemID148124
InChIKeyZDZOTLJHXYCWBA-VCVYQWHSSA-N
SmilesO[C@@H]1C4=C(C)[C@@H](OC([C@H](O)[C@H]([C@]5=CC=CC=C5)NC(OC(C)(C)C)=O)=O)C[C@@](C(C)4C)(O)[C@@H](OC(C6=CC=CC=C6)=O)[C@@]([C@@]3(OC(C)=O)[C@H](OC3)C[C@@H]2O)([H])[C@]2(C)C1=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO80.79100
ethanol80.79100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight807.88.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.24mL6.19mL12.38mL
5mM0.25mL1.24mL2.48mL
10mM0.12mL0.62mL1.24mL
50mM0.02mL0.12mL0.25mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet