请使用支持JavaScript的浏览器!
主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Compstatin/2585/1/1 mg
产品编号:2585/1
市  场 价:¥4180.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$209.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Compstatin/2585/1/1 mg
商品介绍
Description:C3-bindingprotein,inhibitscomplementactivation
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Complementinhibitor;bindsC3inhibitingproteolyticcleavagebyC3convertase(IC50=28μM)andactivationofclassicalandalternativecomplementpathways(IC50valuesare63and12μMrespectively).Prolongsgraftsurvivalandreduceshyperacuterejectionofexvivopigkidneysperfusedwithhumanbloodandinhibitsinvivoheparin/protamine-inducedcomplementactivationinbaboons.Controlpeptideavailable(Cat.No.3796).

TechnicalData

M.Wt1550.77
FormulaC66H99N23O17S2
SequenceICVVQDWGHHRCT

(Modifications:Thr-13=C-terminalamide,Disulfidebridgebetween2-12)

StorageStoreat-20°C
CASNumber206645-99-0
PubChemID25082538
InChIKeyRDTRHBCZFDCUPW-KWICJJCGSA-N
Smiles[H]N[C@@H]([C@@H](C)CC)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC2=CNC=N2)NC(=O)[C@H](CC2=CNC=N2)NC(=O)CNC(=O)[C@H](CC2=CNC3=C2C=CC=C3)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)C(C)C)C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(N)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleto2mg/mlinwater

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight1550.77.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM0.64mL3.22mL6.45mL
5mM0.13mL0.64mL1.29mL
10mM0.06mL0.32mL0.64mL
50mM0.01mL0.06mL0.13mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet