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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Cilengitide/5870/10/10 mg
产品编号:5870/10
市  场 价:¥3700.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$185.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Cilengitide/5870/10/10 mg
商品介绍
Description:Potentandselectiveinhibitorofintegrinsαvβ3andαvβ5
AlternativeNames:EMD121974
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandselectiveinhibitorofintegrinsαvβ3andαvβ5(IC50valuesare4.1and70nM,respectively).Exhibits~10-foldselectivityovergpIIb/IIIa.IncreasesendothelialmonolayerpermeABIlity.Alsoexhibitsantiangiogenicactivity.

TechnicalData

M.Wt588.66
FormulaC27H40N8O7
SequenceRGDFV

(Modifications:Phe-4=D-Phe,Val-5=Me-Val,Cyclizedl)

StorageStoreat-20°C
CASNumber188968-51-6
PubChemID176873
InChIKeyAMLYAMJWYAIXIA-VWNVYAMZSA-N
SmilesCC(C)[C@H]1C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](C(=O)N1C)CC2=CC=CC=C2)CC(=O)O)CCCN=C(N)N

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleto10mg/mlinwater

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight588.66.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.7mL8.49mL16.99mL
5mM0.34mL1.7mL3.4mL
10mM0.17mL0.85mL1.7mL
50mM0.03mL0.17mL0.34mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet