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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Calcineurin Autoinhibitory Peptide/1891/1/1 mg
产品编号:1891/1
市  场 价:¥4180.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>蛋白酶类>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$209.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Calcineurin Autoinhibitory Peptide/1891/1/1 mg
商品介绍
Description:Selectivecalcineurininhibitor
AlternativeNames:Autoinhibitorypeptide457-482
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveinhibitorofCa2+-calmodulin-dependentproteinphosphatase(calcineurin)(IC50~10μM).DoesnotinhibitPP1,PP2AorCaMkinaseII(IC50>100mM).

TechnicalData

M.Wt2930.34
FormulaC124H205N39O39S2
SequenceITSFEEAKGLDRINERMPPRRDAMP
StorageDesiccateat-20°C
CASNumber148067-21-4
PubChemID90488720
InChIKeyJRQDGUSHUYLSHC-TVQDNDAUSA-N
Smiles[H]N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleto1mg/mlinwater

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight2930.34.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM0.34mL1.71mL3.41mL
5mM0.07mL0.34mL0.68mL
10mM0.03mL0.17mL0.34mL
50mM0.01mL0.03mL0.07mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet