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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/(S)-CPW 399/1543/10/10 mg
产品编号:1543/10
市  场 价:¥3780.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$189.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/(S)-CPW 399/1543/10/10 mg
商品介绍
Description:Subtype-selectiveweaklydesensitizingAMPAagoNIST
ChemicalName:(S)-α-Amino-2,3,4,5,6,7-hexahydro-2,4-dioxo-1H-cyclopentapyrimidine-1-propanoicacid
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Novelsubtype-selectiveandweaklydesensitizingAMPAreceptorpartialagonist(Kivaluesare44,109,223,1890and2090nMatGluR5,GluR1,GluR2,GluR3andGluR4receptorsrespectively).ExhibitspotentagonistactivityatGluR1andGluR2subunit-containingAMPAreceptors(EC50valuesare24.9and13.9μMrespectively)andisexcitotoxicinvitro.

TechnicalData

M.Wt239.23
FormulaC10H13N3O4
StorageDesiccateat-20°C
Purity≥98%(HPLC)
CASNumber389888-02-2
PubChemID657004
InChIKeyVSGUEKZRMJVQOH-LURJTMIESA-N
SmilesO=C1NC(C2=C(CCC2)N1C[C@H](N)C(O)=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
phosphatebufferedsaline11.9650
water11.9650

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight239.23.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM4.18mL20.9mL41.8mL
5mM0.84mL4.18mL8.36mL
10mM0.42mL2.09mL4.18mL
50mM0.08mL0.42mL0.84mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet