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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/CP 424174/6107/50/50 mg
产品编号:6107/50
市  场 价:¥10500.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$525.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/CP 424174/6107/50/50 mg
商品介绍
Description:InhibitorofIL-1βpost-translationalprocessing;indirectlyinhibitsNLRP3
ChemicalName:N-[[[4-Chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)benzenesulfonamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InhibitorofIL-1βpost-translationalprocessing(IC50=210nM).InhibitstheformationofmatureIL-1β.IndirectlyinhibitsNLRP3.Activeinvivoandorallybioavailable.

LicensingInformation

SoldforresearchpurposesunderagreementfromPfizerInc.

TechnicalData

M.Wt452.99
FormulaC22H29ClN2O4S
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber210825-31-3
PubChemID9911728
InChIKeyYRSBLSHMKVQWHP-UHFFFAOYSA-N
SmilesO=S(C1=CC(C(O)(C)C)=CC=C1)(NC(NC2=C(C(C)C)C=C(Cl)C=C2C(C)C)=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO45.3100
ethanol45.3100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight452.99.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.21mL11.04mL22.08mL
5mM0.44mL2.21mL4.42mL
10mM0.22mL1.1mL2.21mL
50mM0.04mL0.22mL0.44mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet