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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/CITCO/3683/50/50 mg
产品编号:3683/50
市  场 价:¥10700.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$535.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/CITCO/3683/50/50 mg
商品介绍
Description:SelectiveCARagoNIST
ChemicalName:6-(4-Chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde-O-(3,4-dichlorobenzyl)oxime
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Constitutiveandrostanereceptor(CAR)agonist(EC50=49nM).Displays>100-foldselectivityoverPXRreceptorsandnoactivityatLXR,ERα,ERβ,PPAR,RAR,FXR,VDRandTHR.InducesCARnucleartranslocationandexpressionofCYP2B6inhepatocytesinvitro.

CompoundLibraries

CITCOisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt436.74
FormulaC19H12Cl3N3OS
StorageDesiccateat-20°C
Purity≥98%(HPLC)
CASNumber338404-52-7
PubChemID9600409
InChIKeyZQWBOKJVVYNKTL-AUEPDCJTSA-N
SmilesClC(C(Cl)=C4)=CC=C4CO/N=C/C1=C(C3=CC=C(Cl)C=C3)N=C2N1C=CS2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO21.8450
ethanol2.185

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight436.74.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.29mL11.45mL22.9mL
5mM0.46mL2.29mL4.58mL
10mM0.23mL1.14mL2.29mL
50mM0.05mL0.23mL0.46mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet