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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/CCT 031374 hydrobromide/4675/50/50 mg
产品编号:4675/50
市  场 价:¥13700.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$685.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/CCT 031374 hydrobromide/4675/50/50 mg
商品介绍
Description:InhibitsTCF-dependenttranscription;lowersβ-cateninlevels
ChemicalName:1-[1,1'-Biphenyl]-4-yl-2-(2,3-dihydro-9H-imidazo[1,2-a]benzimidazol-9-yl)ethanonehydrobromide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InhibitorofTCF-dependenttranscription.BlocksBIO-inducedβ-cateninstABIlization;reducesnuclearandcytosolicβ-cateninlevelsinmouseL-cells.InhibitsgrowthandreducesTCF-dependenttranscriptioninSW480coloncarcinomacells.

CompoundLibraries

CCT031374hydrobromideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt434.33
FormulaC23H19N3O.HBr
StorageDesiccateatRT
Purity≥98%(HPLC)
CASNumber1219184-91-4
PubChemID18554738
InChIKeyMPILENOYNNNGKO-UHFFFAOYSA-N
SmilesO=C(C4=CC=C(C5=CC=CC=C5)C=C4)CN1C3=C(C=CC=C3)N2C1=NCC2.Br

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO21.7250

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight434.33.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.3mL11.51mL23.02mL
5mM0.46mL2.3mL4.6mL
10mM0.23mL1.15mL2.3mL
50mM0.05mL0.23mL0.46mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet