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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Bengamide B/5273/100U/100 ug
产品编号:5273/100U
市  场 价:¥2580.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$129.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Bengamide B/5273/100U/100 ug
商品介绍
Description:PotentinhibitorofNF-κBactivation
ChemicalName:(6E)-6,7,8,9-Tetradeoxy-N-[(3S,6S)-hexahydro-1-methyl-2-oxo-6-[(1-oxotetradecyl)oxy]-1H-azepin-3-yl]-8-methyl-2-O-methyl-D-gulo-Non-6-enonamide
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentinhibitorofNF-κBactivation(IC50=85nM);decreasesIκBαphosphorylation.AttenuatesLPS-inducednitricoxideproductionandexpressionofTNF-α,IL-6andMCP.SuppressesproliferationofHeLaandHCT116cells.Anti-inflammatoryandantitumor.

TechnicalData

M.Wt598.81
FormulaC32H58N2O8
StorageStoreat-20°C
Purity≥97%(HPLC)
CASNumber104947-69-5
PubChemID6444128
InChIKeyPFRKTXMXGDERHT-UCDUEDMDSA-N
SmilesO=C1N(C)C[C@@H](OC(CCCCCCCCCCCCC)=O)CC[C@@H]1NC([C@H](OC)[C@H](O)[C@@H](O)[C@H](O)/C=C/C(C)C)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO12

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight598.81.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.67mL8.35mL16.7mL
5mM0.33mL1.67mL3.34mL
10mM0.17mL0.83mL1.67mL
50mM0.03mL0.17mL0.33mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet