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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/(±)-Bay K 8644/1544/50/50 mg
产品编号:1544/50
市  场 价:¥14100.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$705.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/(±)-Bay K 8644/1544/50/50 mg
商品介绍
Description:Ca2+channelactivator(L-type)
ChemicalName:1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylicacid,methylester
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

L-typeCa2+channelactivator(EC50=17.3nM).Haspositiveinotropic,vasoconstrictiveandbehavioraleffectsinvivo.Separateenantiomers(R)-(+)-BayK8644and(S)-(-)-BayK8644alsoavailable(Cat.Nos.1545and1546respectively).IncombinationwithBIX-01294(Cat.No.3364),helpsgenerateinducedpluripotentstemcells(iPSCs)frommouseembryonicfibroblasts(MEFs).Inhibitsautophagy.

CompoundLibraries

(±)-BayK8644isalsoofferedaspartoftheTocriscreenStemCellToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt356.3
FormulaC16H15F3N2O4
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber71145-03-4
PubChemID2303
InChIKeyZFLWDHHVRRZMEI-UHFFFAOYSA-N
SmilesCOC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC=C1C(F)(F)F)[N+]([O-])=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO35.63100
ethanol35.63100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight356.3.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.81mL14.03mL28.07mL
5mM0.56mL2.81mL5.61mL
10mM0.28mL1.4mL2.81mL
50mM0.06mL0.28mL0.56mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet