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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/BMS 564929/5274/5/5 mg
产品编号:5274/5
市  场 价:¥2380.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$119.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/BMS 564929/5274/5/5 mg
商品介绍
Description:Highlypotentandmuscle-selectiveandrogenreceptor(AR)agoNIST
ChemicalName:2-Chloro-3-methyl-4-[(7R,7aS)-tetrahydro-7-hydroxy-1,3-dioxo-1H-pyrrolo[1,2-c]imidazol-2(3H)-yl]benzonitrile
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Highlypotentandselectiveandrogenreceptor(AR)agonist(EC50=0.44nM).ExhibitsselectivityforARsoverestrogen,glucocorticoidandmineralocorticoidreceptorsandnosignificantbindingtosteroidhormonebindingglobulinoraromatase.AlsoexhibitsselectivityformuscleoverprostateARs.Activeinvivoandorallybioavailable.

TechnicalData

M.Wt305.72
FormulaC14H12ClN3O3
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber627530-84-1
PubChemID49823417
InChIKeyKEJORAMIZFOODM-UHFFFAOYSA-N
Smiles[H][C@@]12[C@H](O)CCN1C(=O)N(C2=O)C1=CC=C(C#N)C(Cl)=C1C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO30.57100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight305.72.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.27mL16.35mL32.71mL
5mM0.65mL3.27mL6.54mL
10mM0.33mL1.64mL3.27mL
50mM0.07mL0.33mL0.65mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet