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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/BCTC/3875/10/10 mg
产品编号:3875/10
市  场 价:¥3180.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$159.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/BCTC/3875/10/10 mg
商品介绍
Description:TRPV1antagoNIST
ChemicalName:4-(3-Chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]-1-piperazinecarboxamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Orallyeffectivevanilloidreceptor1(TRPV1receptor)antagonist.Inhibitsacid-andcapsaicin-inducedactivationofratTRPV1receptors(IC50valuesare6.0and35nMrespectively).Displaysanalgesicpropertiesinratmodelsofinflammatoryandneuropathicpain.CNSpenetrant.

CompoundLibraries

BCTCisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt372.89
FormulaC20H25ClN4O
StorageStoreatRT
Purity≥98%(HPLC)
CASNumber393514-24-4
PubChemID9929425
InChIKeyROGUAPYLUCHQGK-UHFFFAOYSA-N
SmilesClC1=CC=CN=C1N2CCN(C(NC3=CC=C(C(C)(C)C)C=C3)=O)CC2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO37.29100
ethanol14.9240

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight372.89.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.68mL13.41mL26.82mL
5mM0.54mL2.68mL5.36mL
10mM0.27mL1.34mL2.68mL
50mM0.05mL0.27mL0.54mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet