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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/BAM 7/4810/10/10 mg
产品编号:4810/10
市  场 价:¥3780.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$189.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/BAM 7/4810/10/10 mg
商品介绍
Description:SelectiveBaxactivator;inducesBax-mediatedapoptosis
ChemicalName:3-Methyl-1-(4-phenyl-2-thiazolyl)-1H-pyrazole-4,5-dione4-[2-(2-Ethoxyphenyl)hydrazone]
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Baxactivator(EC50=3.3μM);bindsattheBH3-bindingsite.SelectiveforBaxoverotherantiapoptoticandproapoptoticproteins.TriggersBaxoligomerizationinvitro;inducesBax-mediatedapoptosisinmouseembryonicfibroblasts.

TechnicalData

M.Wt405.47
FormulaC21H19N5O2S
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber331244-89-4
PubChemID5754137
InChIKeyKOCVKGYKBLJEPK-LYBHJNIJSA-N
SmilesCC(/C1=NNC2=C(OCC)C=CC=C2)=NN(C3=NC(C4=CC=CC=C4)=CS3)C1=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO4.0510

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight405.47.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.47mL12.33mL24.66mL
5mM0.49mL2.47mL4.93mL
10mM0.25mL1.23mL2.47mL
50mM0.05mL0.25mL0.49mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet