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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/5-Azacytidine/3842/50/50 mg
产品编号:3842/50
市  场 价:¥1180.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$59.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/5-Azacytidine/3842/50/50 mg
商品介绍
Description:DNAmethyltransferaseinhibitor
ChemicalName:4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

DNAmethyltransferaseinhibitor.IncorporatesintoDNAformingcovalentadductswithcellularDNMT1,depletingenzymeactivity.Inducesdemethylationandreactivationofsilencedgenes.Improvestheefficiencyofreprogrammingofstemcells;inducesdifferentiationofmesenchymalstemcellsintocardiomyocytes.

CompoundLibraries

5-AzacytidineisalsoofferedaspartoftheTocriscreenPlus,TocriscreenEpigeneticsToolbox,TocriscreenLibraryofFDA-ApprovedCompoundsandTocriscreenStemCellToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt244.2
FormulaC8H12N4O5
StorageStoreatRT
Purity≥98%(HPLC)
CASNumber320-67-2
PubChemID9444
InChIKeyNMUSYJAQQFHJEW-KVTDHHQDSA-N
SmilesO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C(N=C(N)N=C2)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO24.42100
water12.2150

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight244.2.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM4.1mL20.48mL40.95mL
5mM0.82mL4.1mL8.19mL
10mM0.41mL2.05mL4.1mL
50mM0.08mL0.41mL0.82mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet