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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Atiprimod dihydrochloride/4580/10/10 mg
产品编号:4580/10
市  场 价:¥4180.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$209.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Atiprimod dihydrochloride/4580/10/10 mg
商品介绍
Description:JAK2inhibitor
ChemicalName:N,N-Diethyl-8,8-dipropyl-2-azaspiro[4.5]decane-2-propanaminedihydrochloride
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

JAK2inhibitor(IC50=397nM).AlsoinhibitsSTAT3andSTAT5phosphorylation.InhibitscellgrowthandinducesapoptosisincellsexpressingtheJAK2V617Fmutation.

TechnicalData

M.Wt409.52
FormulaC22H44N2.2HCl
StorageDesiccateatRT
CASNumber130065-61-1
PubChemID166556
InChIKeyMOUZYBYTICOTFQ-UHFFFAOYSA-N
SmilesCCCC1(CCC)CCC2(CN(CCCN(CC)CC)CC2)CC1.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO4.110mMwithgentlewarming
water20.4850

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight409.52.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.44mL12.21mL24.42mL
5mM0.49mL2.44mL4.88mL
10mM0.24mL1.22mL2.44mL
50mM0.05mL0.24mL0.49mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet