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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Apicidin/4846/1/1 mg
产品编号:4846/1
市  场 价:¥2580.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$129.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Apicidin/4846/1/1 mg
商品介绍
Description:Potenthistonedeacetylaseinhibitor
ChemicalName:Cyclo[(2S)-2-Amino-8-oxodecanoyl-1-methoxy-L-tryptophyl-L-isoleucyl-(2R)-2-piperidinecarbonyl]
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potenthistonedeacetylase(HDAC)inhibitor(IC50=0.7nMinanenzymeactivityassay).Antiangiogenicandanti-invasive;blocksproliferationofhumanstomachandbreastcancercells.Inducesapoptosisandautophagyinhumanoralsquamouscarcinomacells.

TechnicalData

M.Wt623.78
FormulaC34H49N5O6
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber183506-66-3
PubChemID44593387
InChIKeyJWOGUUIOCYMBPV-VWIQTCEGSA-N
SmilesCON2C1=CC=CC=C1C(C[C@@H](C(N[C@@H]([C@H](C)CC)C3=O)=O)NC([C@H](CCCCCC(CC)=O)NC([C@]4([H])N3CCCC4)=O)=O)=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO0.941.5
ethanol0.941.5

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight623.78.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.6mL8.02mL16.03mL
5mM0.32mL1.6mL3.21mL
10mM0.16mL0.8mL1.6mL
50mM0.03mL0.16mL0.32mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet