请使用支持JavaScript的浏览器!
主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Apcin/5747/10/10 mg
产品编号:5747/10
市  场 价:¥2980.00
场      地:美国(厂家直采)
产品分类: 分子类>核酸酶类>连接酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$149.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Apcin/5747/10/10 mg
商品介绍
Description:Cdc20inhibitor;inhibitsCdc20-substrateinteraction
ChemicalName:3-(2-Methyl-5-nitroimidazol-1-yl)-N-(2,2,2-trichloro-1-phenylaminoethyl)propionamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Cdc20inhibitor;inhibitsCdc20-substrateinteraction.Blockssubstrate-mediatedCdc20loADIngontotheanaphase-promotingcomplex(APC).InhibitsAPC-dependentubiquitylation.ProlongsmitoticdurationinRPE1cellsincombinationwithproTAME(prodrugofTAME(Cat.No.4506))invitro.

TechnicalData

M.Wt438.65
FormulaC13H14Cl3N7O4
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber300815-04-7
PubChemID2830389
InChIKeyZEXHXVOGJFGTRX-UHFFFAOYSA-N
SmilesCC1=NC=C([N+]([O-])=O)N1CCOC(NC(C(Cl)(Cl)Cl)NC2=NC=CC=N2)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO43.87100
ethanol2.195mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight438.65.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.28mL11.4mL22.8mL
5mM0.46mL2.28mL4.56mL
10mM0.23mL1.14mL2.28mL
50mM0.05mL0.23mL0.46mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet