请使用支持JavaScript的浏览器!
主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Andrographolide/4626/50/50 mg
产品编号:4626/50
市  场 价:¥1900.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$95.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Andrographolide/4626/50/50 mg
商品介绍
Description:InhibitsNFκB;blocksandrogenreceptor(AR)expression
ChemicalName:(3E,4S)-3-[2-[(1R,4aS,5R,6R,8aS)-Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-2(3H)-furanone
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InhibitorofNF-κBsignaling;alsoattenuatesconcanavaline-inducedIFNγproductioninmurineTcells(IC50=1.7μM).Blocksandrogenreceptor(AR)expressioninAR-expressingC4-2cells.ActivatesNrf2inBEAS-2Bcellsinresponsetocigarettesmokeextract.

TechnicalData

M.Wt350.45
FormulaC20H30O5
StorageStoreat-20°C
Purity≥99%(HPLC)
CASNumber5508-58-7
PubChemID452937
InChIKeyBOJKULTULYSRAS-UQZPWQSVSA-N
SmilesC=C1CC[C@@]([C@@](CO)(C)[C@H](O)CC3)([H])[C@]3(C)[C@@H]1C/C=C2[C@H](O)COC/2=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO35.05100
ethanol3.510

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight350.45.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.85mL14.27mL28.53mL
5mM0.57mL2.85mL5.71mL
10mM0.29mL1.43mL2.85mL
50mM0.06mL0.29mL0.57mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet