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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Bioymifi/5372/5/5 mg
产品编号:5372
市  场 价:¥2180.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$109.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Bioymifi/5372/5/5 mg
商品介绍
Description:DR5(TRAILreceptor)agoNIST;inducesapoptosis
ChemicalName:5-[5-[[(5Z)-3-(4-Bromophenyl)-2-imino-4-oxo-5-thiazolidinylidene]methyl]-2-furanyl]-1H-isoindole-1,3(2H)-dione
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

DR5(TRAILreceptor)agonist.DirectlybindsextracellulardomainofDR5(Kd=1.2μM)andinducestheformationofDR5aggregates.Inducesapoptosisofglioblastomacells.

TechnicalData

M.Wt494.32
FormulaC22H12BrN3O4S
StorageStoreat+4°C
Purity≥97%(HPLC)
CASNumber1420071-30-2
PubChemID70678419
InChIKeyULBOWKXOFOTCMU-NLDKGBHCSA-N
SmilesBrC1=CC=C(N3C(/C(SC3=N)=C/C2=CC=C(C4=CC=C(C(NC5=O)=O)C5=C4)O2)=O)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO0.491mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight494.32.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.02mL10.11mL20.23mL
5mM0.4mL2.02mL4.05mL
10mM0.2mL1.01mL2.02mL
50mM0.04mL0.2mL0.4mL