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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/C-DIM 12/5821/10/10 mg
产品编号:5821
市  场 价:¥2700.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$135.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/C-DIM 12/5821/10/10 mg
商品介绍
Description:Nurr1activator;inhibitsNF-κB-dependentgeneexpression
ChemicalName:3,3'-[(4-Chlorophenyl)methylene]bis[1H-indole]
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Nurr1activator.InhibitsNF-κBandcytokineexpressioninmicroglialcellsbystABIlizingnuclearcorepressorproteins,whichreducesbindingofp65toinflammatorygenepromoters.NeuroprotectiveinamouseParkinson'sdiseasemodel.Orallybioavailable.

TechnicalData

M.Wt356.85
FormulaC23H17ClN2
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber178946-89-9
PubChemID5302583
InChIKeyLTLRXTDMXOFBDW-UHFFFAOYSA-N
SmilesClC1=CC=C(C(C2=CNC3=C2C=CC=C3)C4=CNC5=C4C=CC=C5)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO35.69100
ethanol35.69100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight356.85.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.8mL14.01mL28.02mL
5mM0.56mL2.8mL5.6mL
10mM0.28mL1.4mL2.8mL
50mM0.06mL0.28mL0.56mL