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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Lenalidomide/6305/100/100 mg
产品编号:6305
市  场 价:¥900.00
场      地:美国(厂家直采)
产品分类: 分子类>核酸酶类>连接酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$45.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Lenalidomide/6305/100/100 mg
商品介绍
Description:Cereblonbinder;inducesubiquitinationanddegradationofCK1αbyE3ubiquitinligase
ChemicalName:3-(4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Thalidomideanalog.Immunemodulatorydrugandcereblonbindingcompound.Inducesubiquitinationanddegradationofcaseinkinase(CK)1αbytheE3ubiquitinligaseCRL4CRBN.AlsoTNF-αinhibitorandangiogenesisinhibitor.

TechnicalData

M.Wt259.26
FormulaC13H13N3O3
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber191732-72-6
PubChemID216326
InChIKeyGOTYRUGSSMKFNF-UHFFFAOYSA-N
SmilesNC1=C2CN(C(C2=CC=C1)=O)C3CCC(NC3=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO25.93100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight259.26.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.86mL19.29mL38.57mL
5mM0.77mL3.86mL7.71mL
10mM0.39mL1.93mL3.86mL
50mM0.08mL0.39mL0.77mL