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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Pomalidomide/6302/10/10 mg
产品编号:6302
市  场 价:¥2780.00
场      地:美国(厂家直采)
产品分类: 分子类>核酸酶类>连接酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$139.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Pomalidomide/6302/10/10 mg
商品介绍
Description:Cereblonubiquitinationinhibitor;alsoTNF-αinhibitorandantiangiogenic
ChemicalName:4-Amino-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentTNF-αinhibitor(IC50=13nM).AlsopotentlyinhibitsIL-2(EC50=8nM).Thalidomidederivative.Bindscereblonandinhibitsitsubiquitination.ExhibitsantiproliferativeeffectsinaNamalwalymphomacellline.Antiangiogenic.

TechnicalData

M.Wt273.24
FormulaC13H11N3O4
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber19171-19-8
PubChemID134780
InChIKeyUVSMNLNDYGZFPF-UHFFFAOYSA-N
SmilesNC1=CC=CC2=C1C(N(C2=O)C3CCC(NC3=O)=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO27.32100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight273.24.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.66mL18.3mL36.6mL
5mM0.73mL3.66mL7.32mL
10mM0.37mL1.83mL3.66mL
50mM0.07mL0.37mL0.73mL