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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/AAQ chloride/5462/10/10 mg
产品编号:5462
市  场 价:¥3700.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$185.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/AAQ chloride/5462/10/10 mg
商品介绍
Description:PhotoswitchableKvchannelblocker
ChemicalName:N,N,N-Triethyl-2-oxo-2-[[4-[2-[4-[(1-oxo-2-propen-1-yl)amino]phenyl]diazenyl]phenylamino]ethanaminiumchloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PhotoswitchableKvchannelblocker(IC50valuesare2and64μMat500nmand380nmrespectively).Switchesconformationfromcistotransat500nmandtranstocisat380nm.ExhibitsminimalactivityatNav1.2andL-typeCa2+channels.Stimulatesactionpotentialfiringofhippocampalneuronsinvitroat500nmandrestoresvisualresponsivenessinblindmiceat380nm.

LicensingInformation

SoldunderlicensefromPhotoswitchBiosciences,Inc.

TechnicalData

M.Wt443.97
FormulaC23H30ClN5O2
StorageStoreat-20°C
Purity≥98%(HPLC)
PubChemID91826090
InChIKeyCTVKLIGDHHKPIB-UHFFFAOYSA-N
SmilesO=C(C=C)NC(C=C2)=CC=C2/N=N/C1=CC=C(NC(C[N+](CC)(CC)CC)=O)C=C1.[Cl-]

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO8.8820

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight443.97.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.25mL11.26mL22.52mL
5mM0.45mL2.25mL4.5mL
10mM0.23mL1.13mL2.25mL
50mM0.05mL0.23mL0.45mL