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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/(Z)-4-Hydroxytamoxifen/3412/10/10 mg
产品编号:3412
市  场 价:¥3500.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$175.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/(Z)-4-Hydroxytamoxifen/3412/10/10 mg
商品介绍
Description:Metaboliteoftamoxifen(Cat.No.0999)
AlternativeNames:4-OH-TAM
ChemicalName:4-[(1Z)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

EstrogenreceptorantagoNIST.Tamoxifen(Cat.No.0999)metabolite;exhibitsgreaterpotencythantheparentcompound.Chemotherapeuticagent.Alsoactivatesintein-linkedinactiveCas9,reducingoff-targetCRISPR-mediatedgeneediting;systemhas~25-foldhigherspecificitythanwtCas9.

TechnicalData

M.Wt387.51
FormulaC26H29NO2
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber68047-06-3
PubChemID449459
InChIKeyTXUZVZSFRXZGTL-QPLCGJKRSA-N
SmilesCCC(C3=CC=CC=C3)=C(C2=CC=C(OCCN(C)C)C=C2)/C1=CC=C(O)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO38.75100
ethanol19.3850

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight387.51.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.58mL12.9mL25.81mL
5mM0.52mL2.58mL5.16mL
10mM0.26mL1.29mL2.58mL
50mM0.05mL0.26mL0.52mL