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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Brefeldin A/1231/5/5 mg
产品编号:1231
市  场 价:¥2780.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$139.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Brefeldin A/1231/5/5 mg
商品介绍
Description:DisruptsproteintranslocationtoGolgi
ChemicalName:1,6,7,8,9,11aβ,12,13,14,14αa-Decahydro-1β,13α-dihydroxy-6β-methyl-4H-cyclopent(f)oxacyclotridecin-4-one
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

ReversIBLeinhibitorofproteintranslocationfromtheendoplasmicreticulum(ER)totheGolgiapparatus.BlocksbindingofADP-ribosylationfactortotheGolgiapparatusandinhibitsGDP-GTPexchange.Canbeusedtoinduceautophagyinmammaliancells.AlsoenhancesCRISPR-mediatedhomology-directedrepair(HDR)efficiency~2-foldwhenappliedat100nM,inhumaninducedpluripotentstemcells(iPSCs).

CompoundLibraries

BrefeldinAisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt280.36
FormulaC16H24O4
StorageDesiccateat-20°C
Purity≥98%(HPLC)
CASNumber20350-15-6
PubChemID6436187
InChIKeyKQNZDYYTLMIZCT-KFKPYADVSA-N
Smiles[H][C@]1(C)CCCC=CC2C[C@H](O)C[C@H]2[C@H](O)C=CC(=O)O1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO14.0250
ethanol2.810

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight280.36.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.57mL17.83mL35.67mL
5mM0.71mL3.57mL7.13mL
10mM0.36mL1.78mL3.57mL
50mM0.07mL0.36mL0.71mL