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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Acyclovir/2513/50/50 mg
产品编号:2513/50
市  场 价:¥1900.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$95.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Acyclovir/2513/50/50 mg
商品介绍
Description:InhibitsviralDNApolymerase;antiherpeticagent
AlternativeNames:Aciclovir,Acycloguanosine
ChemicalName:2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Antiviralagent,activeagainstherpessimplexvirusesHSV-1andHSV-2(EC50valuesare0.85and0.86μMrespectively).InterfereswithviralDNApolymerizationthroughcompetitiveinhibitionwithguanosinetriphosphate.InducesapoptosisincellstransfectedwithHSV-TK(suicidalgenetherapy).

CompoundLibraries

AcyclovirisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt225.21
FormulaC8H11N5O3
StorageStoreatRT
Purity≥99%(HPLC)
CASNumber59277-89-3
PubChemID2022
InChIKeyMKUXAQIIEYXACX-UHFFFAOYSA-N
SmilesNC1=NC(=O)C2=C(N1)N(COCCO)C=N2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
1eq.HCl11.2650
DMSO4.520

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight225.21.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM4.44mL22.2mL44.4mL
5mM0.89mL4.44mL8.88mL
10mM0.44mL2.22mL4.44mL
50mM0.09mL0.44mL0.89mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet